Flexoplex Joint Relief Supplement

What is Flexoplex?

Flexoplex Joint Relief Supplement

Flexoplex is another very popular joint pain relief supplement.  Some of the benefits claimed by the Flexplex manufacturers include:

  • Reduction in joint pain, inflammation and stiffness;
  • maximizes comfort, mobility & flexibility;
  • Repairs and regenerates damaged tissue & cartilage;
  • Stops future joint wear and tear.

According to the Flexoplex website (flexoplexstore.com) they claim that 93% of users of Flexoplex enjoyed a significant reduction in their joint pain and inflammation within the first 4 weeks.  Click here to shop for Flexoplex on Amazon.com

Another joint pain relief supplement which appears to have many positive reviews is known as Joint Genesis by BIODYNAMIX.  Be sure to check out our review of Joint Genesis by clicking here:  Joint Genesis Review.

Does Flexoplex Have Positive User Reviews?

As Amazon.com is the largest online retailer in the world it is often a great resource for analyzing customer reviews.  

At the time of writing this article there have been 537 user reviews of Flexoplex on the Amazon.com website.  The average rating is 3.9 stars out of 5.   Click here to view the Amazon.com product reviews for Flexoplex. 

At the time of this article the breakdown of the reviews are distributed as follows:

  •  49% – 5 stars;
  • 20% – 4 stars;
  • 12% – 3 stars;
  • 8% – 2 stars; and
  • 11% – 1 star

Many of those leaving positive reviews for Flexoplex expressed that they did notice a definite reduction in joint pain and improvements in reducing stiffness of the joints.

Of the negative reviews on Amazon.com many of the complaints include:

  •  That the product did not work for them in terms of pain relief;
  • That the recommended dosage of 4 tablets per day made the product expensive to use;
  • That the supplement caused them to have constipation and gas;
  • That the supplement caused them to have headaches.

What is Flexoplex Made Of?

According to the Flexoplex website the supplement is a complete proprietary formula which consists of potent extracts known to alleviate joint pain. 

As stated on their website, some of the natural ingredients within the proprietary formula are:

  • Chondroitin Sulfate;
  • Glucosamine Sulfate;
  • Cat’s Claw Bark;
  • Boswellia Serrata;
  • Bromelain;
  • Methylsulfonylmethane (MSM)

Scientific Studies Referred to by Flexoplex

Glucosamine Sulfate

Glucosamine sulfate supplements are mostly derived from chitin, which is the hard outer shell of shrimp, lobster, and crab.  Flexoplex refers to the 2009 study performed by the department of internal medicine, University of Siena, Siena, Itlay,  in which it was found that during a 12 week study on knee osteoarthritis patients found that 1500 mg of Glucosamine Sulfate daily, significantly relieved pain symptoms.  Click the citation belowto review the said study.

flexoplex joint relief supplement

Chondroitin Sulfate

Chondroitin Sulfate can come from natural sources such as shark or bovine cartilage. Flexoplex refers to the 2011 study, in which it was concluded that chondroitin and glucosamine reduced pain and improved function in people with osteoarthritis.  Click the citation below to review the said study.

flexoplex joint relief supplement

Cat's Claw Bark

Cat’s claw is a woody vine native to the Amazon rain forest.  Flexoplex refers to the 2001 four week study, in which showed that taking cat’s claw daily decreased pain in knee osteoarthritis patients.  Click the citation below to review the said study.

flexoplex joint relief supplement

Boswellia Serrata

Boswellia is a herbal extract taken from the Boswellia serrata tree.  Flexoplex refers to a 2019, 120 day study which found that Boswellia Serrata led to less pain, reduced stiffness, and enhanced flexibility in knee osteoarthritis patients.  Click here to review the said study.


Bromelain is a group of enzymes found in the fruit and stem of the pineapple plant.  Flexoplex refers to a 2021 molecular study, which showed that bromelain prevents cartilage degradation and decreases inflammation in arthritis.   Click on the citation below to review the said study.

flexoplex joint relief supplement

Methylsulfonylmethane (MSM)

Methylsulfonylmethane (MSM) is found in protein-rich foods, such as eggs, meat, poultry and fish.  Flexoplex refers to a 2005 12 week study which concluded that daily intake of MSM decreased pain, stiffness, and swelling in knee osteoarthritis.  Click on the citation below to review the said study.

flexoplex joint relief supplement


In summary Flexoplex appears to have approximately 69% 5 star, or 4 star reviews.  The scientific studies referred to on the Flexoplex website appear to indicate that the active ingredients within Flexoplex may offer some benefits with relief of joint pain, stiffness and inflammation.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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